Tocris/Tubastatin A hydrochloride/6270/10/10 mg188bio精品生物—专注于实验室精品爆款的电商平台

BiologicalActivity

PotentHDAC6inhibitor(IC₅₀=0.015μM).ExhibitssomeselectivelyforHDAC6overHDAC8and1(IC₅₀valuesare0.854and16.4μM,respectively).Induceselevatedlevelsofα-tubulinandprotectsagainstglutathione-inducedoxidativestressinprimaryneuronalcellculture.

TechnicalData

M.Wt	371.86
Formula	C₂₀H₂₁N₃O₂.HCl
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	1310693-92-5
PubChemID	57336514
InChIKey	LJTSJTWIMOGKRJ-UHFFFAOYSA-N
Smiles	CN1CCC2=C(C3=CC=CC=C3N2CC4=CC=C(C(NO)=O)C=C4)C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	3.72	10mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight371.86.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.69mL	13.45mL	26.89mL
5mM	0.54mL	2.69mL	5.38mL
10mM	0.27mL	1.34mL	2.69mL
50mM	0.05mL	0.27mL	0.54mL

MolarityCalculator

Calculatethemass,volume,orconcentrationrequiredforasolution.

ReconstitutionCalculator

Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.

Volume(toaddtovial)

DilutionCalculator

Calculatethedilutionrequiredtoprepareastocksolution.