Tocris/CC 401 dihydrochloride/6258/10/10 mg188bio精品生物—专注于实验室精品爆款的电商平台

BiologicalActivity

HighaffinityJNKinhibitor(K_ivaluesare25-50nM).InhibitsJNKviacompetitivebindingoftheATP-bindingsiteofactive,phosphorylatedJNK.Exhibits>40-foldselectivityforJNKoverp38,ERK,IKK2,proteinkinaseC,LckandZAP70.Hepatoprotective.AlsoinhibitsHCMVreplication.

TechnicalData

M.Wt	461.39
Formula	C₂₂H₂₄N₆O.2HCl
Storage	Storeat-20°C
Purity	≥98%(HPLC)
PubChemID	66576998
InChIKey	LDUPODIOUWRGCQ-UHFFFAOYSA-N
Smiles	N1(CCCCC1)CCOC2=CC=CC(C3=NNC4=CC=C(C5=NN=CN5)C=C34)=C2.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	46.14	100
	water	46.14	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight461.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.17mL	10.84mL	21.67mL
5mM	0.43mL	2.17mL	4.33mL
10mM	0.22mL	1.08mL	2.17mL
50mM	0.04mL	0.22mL	0.43mL

MolarityCalculator

Calculatethemass,volume,orconcentrationrequiredforasolution.

ReconstitutionCalculator

Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.

Volume(toaddtovial)

DilutionCalculator

Calculatethedilutionrequiredtoprepareastocksolution.