Tocris/AC 265347/6165/10/10 mg188bio精品生物—专注于实验室精品爆款的电商平台

BiologicalActivity

CaSRbiasedallostericmodulator(pEC₅₀=7.8-8.1).Calcimimetic.DisplaysABIlitytobiassignallingtowardstheaccumulationofPERK1/2andIP₁.Reducesparathyroidhormone(PTH)levelsinratserumwithoutinducingthereleaseofcalcitonin.ExhibitsnosignificantactivationofhumanGABA_BortypeIPTHreceptors.Orallyactive.

TechnicalData

M.Wt	283.39
Formula	C₁₇H₁₇NOS
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	1253901-26-6
PubChemID	52943938
InChIKey	IGSZVEPQZANNAB-UHFFFAOYSA-N
Smiles	CC1=CC(C)=C(C(O)(C2=NC3=CC=CC=C3S2)C)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	28.34	100
	ethanol	28.34	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight283.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.53mL	17.64mL	35.29mL
5mM	0.71mL	3.53mL	7.06mL
10mM	0.35mL	1.76mL	3.53mL
50mM	0.07mL	0.35mL	0.71mL

MolarityCalculator

Calculatethemass,volume,orconcentrationrequiredforasolution.

ReconstitutionCalculator

Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.

Volume(toaddtovial)

DilutionCalculator

Calculatethedilutionrequiredtoprepareastocksolution.