Description:NegativeControlforMZ1
ChemicalName:(2S,4S)-1-((S)-2-(tert-butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
NegativeControlforMZ1(Cat.No.6154).ExhibitsnosignificantVHLbindingaffinity.
LicensingInformation
SoldunderlicencefromtheUniversityofDundee
ExternalPortalInformation
Chemicalprobes.orgisaportalthatoffersindependentguidanceontheselectionand/orapplicationofsmallmoleculesforresearch.TheuseofMZ1isreviewedonthechemicalprobeswebsite.
TechnicalData
| M.Wt | 1002.64 |
| Formula | C49H60ClN9O8S2 |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 1797406-72-4 |
| PubChemID | 124201820 |
| InChIKey | PTAMRJLIOCHJMQ-HADAFJFFSA-N |
| Smiles | CC1=C(C2=C(N3C(C)=NN=C3[C@@H](N=C2C4=CC=C(C=C4)Cl)CC(NCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N5C[C@H](C[C@H]5C(NCC6=CC=C(C7=C(N=CS7)C)C=C6)=O)O)=O)=O)=O)S1)C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM |
|---|
| Solubility |
|---|
| DMSO | 100.26 | 100 |
| ethanol | 100.26 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight1002.64.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|
| 1mM | 1mL | 4.99mL | 9.97mL |
| 5mM | 0.2mL | 1mL | 1.99mL |
| 10mM | 0.1mL | 0.5mL | 1mL |
| 50mM | 0.02mL | 0.1mL | 0.2mL |
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