Tocris/WZB 117/6143/5/5 mg188bio精品生物—专注于实验室精品爆款的电商平台

BiologicalActivity

GLUTinhibitor(K_i(app)valuesare0.2,10and10μMforGLUT4,GLUT1andGLUT3,respectively).Competitiveinhibitorofnetglucoseuptakebutanoncompetitiveinhibitorofsugareffluxfromcells.Inhibitspassivesugartransportinhumanerythrocytesandcancercelllines.Attenuateserythrocyte3-O-metylglucose(3MG)uptakeinvitro(K_i=6μM).Suppressestumorgrowthinanudemousemodel.

TechnicalData

M.Wt	368.31
Formula	C₂₀H₁₃FO₆
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1223397-11-2
PubChemID	46830365
InChIKey	FRSWCCBXIHFKKY-UHFFFAOYSA-N
Smiles	OC1=CC=CC(C(OC2=C(C(F)=CC=C2)OC(C3=CC(O)=CC=C3)=O)=O)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	36.83	100
	ethanol	36.83	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight368.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.72mL	13.58mL	27.15mL
5mM	0.54mL	2.72mL	5.43mL
10mM	0.27mL	1.36mL	2.72mL
50mM	0.05mL	0.27mL	0.54mL

MolarityCalculator

Calculatethemass,volume,orconcentrationrequiredforasolution.

ReconstitutionCalculator

Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.

Volume(toaddtovial)

DilutionCalculator

Calculatethedilutionrequiredtoprepareastocksolution.