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Tocris/TC AC 28/6105/1/1 mg
  • Tocris/TC AC 28/6105/1/1 mg

Tocris/TC AC 28/6105/1/1 mg

价格: ¥1068.00 市场价: 1780.00
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货号: 6105
品牌: Tocris
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    • Description:HighaffinityBETbromodomainligand
      ChemicalName:6-(1H-Indol-4-yl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-aceticacidmethylester
      Purity:≥98%(HPLC)
      BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

      BiologicalActivity

      HighaffinityBETbromodomainligand(Kdvaluesare40and800nMforBrd2(2)andBrd2(1),respectively).Exhibits20-foldselectivelyforthesecondoverthefirstbromodomain.

      LicensingInformation

      SoldunderlicencefromtheUniversityofDundee.

      TechnicalData

      M.Wt415.44
      FormulaC23H21N5O3
      StorageStoreat-20°C
      Purity≥98%(HPLC)
      CASNumber1809296-92-1
      PubChemID118121364
      InChIKeyRARZHTSXOQRRPR-UHFFFAOYNA-N
      SmilesCOC(CC1N=C(C2=CC(OC)=CC=C2N3C(C)=NN=C13)C4=C5C=CNC5=CC=C4)=O

      Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

      AllTocrisproductsareintendedforlaboratoryresearchuseonly.

      SolubilityData

      SolventMaxConc.mg/mLMaxConc.mM
      Solubility
      DMSO2.085mMwithgentlewarming
      ethanol2.085mMwithgentlewarming

      PreparingStockSolutions

      Thefollowingdataisbasedontheproductmolecularweight415.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

      Concentration/SolventVolume/Mass1mg5mg10mg
      1mM2.41mL12.04mL24.07mL
      5mM0.48mL2.41mL4.81mL
      10mM0.24mL1.2mL2.41mL
      50mM0.05mL0.24mL0.48mL