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Tocris/Lalistat 1/6098/10/10 mg
  • Tocris/Lalistat 1/6098/10/10 mg

Tocris/Lalistat 1/6098/10/10 mg

价格: ¥2220.00 市场价: 3700.00

货号: 6098
品牌: Tocris
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    • Description:Potentandselectivelysosomalacidlipase(LAL)inhibitor
      ChemicalName:4-(Piperidin-1-yl)-1,2,5-thiADIazol-3-ylmorpholine-4-carboxylate
      Purity:≥98%(HPLC)
      BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

      BiologicalActivity

      Potentandselectivelysosomalacidlipase(LAL)inhibitor(IC50=68nM).Exhibitsnosignificantactivityagainstpancreaticlipaseorlipoproteinlipaseat10μMconcentration.BlocksLAL-mediatedlipidhydrolysisofacetylatedLDLandreduceseffluxofcholesterolfromlipid-loadedcellsresultinginincreasedcellularcholesterolesterlevels.

      TechnicalData

      M.Wt298.36
      FormulaC12H18N4O3S
      StorageStoreat+4°C
      Purity≥98%(HPLC)
      CASNumber501104-16-1
      PubChemID648404
      InChIKeyGKOPFXFKPASEFI-UHFFFAOYSA-N
      SmilesO=C(OC1=NSN=C1N2CCCCC2)N3CCOCC3

      Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

      AllTocrisproductsareintendedforlaboratoryresearchuseonly.

      SolubilityData

      SolventMaxConc.mg/mLMaxConc.mM
      Solubility
      DMSO29.84100
      ethanol29.84100

      PreparingStockSolutions

      Thefollowingdataisbasedontheproductmolecularweight298.36.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

      Concentration/SolventVolume/Mass1mg5mg10mg
      1mM3.35mL16.76mL33.52mL
      5mM0.67mL3.35mL6.7mL
      10mM0.34mL1.68mL3.35mL
      50mM0.07mL0.34mL0.67mL