BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Selectiveflavivirusinhibitor.Adenosineanalog.Inhibitsdenguevirus(EC50=0.64μM),hepatitisCvirusandcellularentryofZikavirus.ReducesincreasesofcytokinesandNS1andpreventsdeathindengue-infectedmice.Activeinvivo.Orallybioavailable.
TechnicalData
M.Wt | 290.27 |
Formula | C13H14N4O4 |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 1044589-82-3 |
PubChemID | 44633776 |
InChIKey | NKRAIOQPSBRMOV-NRMKKVEVSA-N |
Smiles | NC1=C2C=CN(C2=NC=N1)[C@@H]3O[C@@H]([C@H]([C@@]3(C#C)O)O)CO |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM |
---|
Solubility |
---|
DMSO | 5.81 | 20 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight290.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|
1mM | 3.45mL | 17.23mL | 34.45mL |
5mM | 0.69mL | 3.45mL | 6.89mL |
10mM | 0.34mL | 1.72mL | 3.45mL |
50mM | 0.07mL | 0.34mL | 0.69mL |