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Tocris/B I09/6009/10/10 mg
  • Tocris/B I09/6009/10/10 mg

Tocris/B I09/6009/10/10 mg

价格: ¥2388.00 市场价: 3980.00

货号: 6009
品牌: Tocris
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    • Description:IRE1endonucleaseinhibitor;cellpermeable
      ChemicalName:7-(1,3-Dioxan-2-yl)-1,2,3,4-tetrahydro-8-hydroxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one
      Purity:≥98%(HPLC)
      BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

      BiologicalActivity

      IRE-1RNaseinhibitor(IC50=1.23μM).InhibitsIRE-1/XBP1pathway.Cellpermeable.Inhibitsgrowthofhumanchroniclymphocyticleukemia(CLL)cellsinvitroandpromotesCLLregressioninamousemodel.

      TechnicalData

      M.Wt303.31
      FormulaC16H17NO5
      StorageStoreat-20°C
      Purity≥98%(HPLC)
      CASNumber1607803-67-7
      PubChemID86290458
      InChIKeyUYYMWNUDIOPESF-UHFFFAOYSA-N
      SmilesOC1=CC=C2C3=C(C(OC2=C1C4OCCCO4)=O)CNCC3

      Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

      AllTocrisproductsareintendedforlaboratoryresearchuseonly.

      SolubilityData

      SolventMaxConc.mg/mLMaxConc.mM
      Solubility
      DMSO15.1750

      PreparingStockSolutions

      Thefollowingdataisbasedontheproductmolecularweight303.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

      Concentration/SolventVolume/Mass1mg5mg10mg
      1mM3.3mL16.48mL32.97mL
      5mM0.66mL3.3mL6.59mL
      10mM0.33mL1.65mL3.3mL
      50mM0.07mL0.33mL0.66mL