Mitomycin C is an anti-neoplastic antibiotic, DNA inter-strand,cross-linking alkylating agent that targets guanine nucleoside inthe sequence 5 CpG-3 . It produces oxygen radicals and ispreferentially toxic to hypoxic cells. It is used to generatemitotically inactive feeder cells used in cell culture systems,such as mitotically inactive fibroblast used in embryonic stemcell (ESC) systems. Soluble in methanol and water.
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