G418 sulfate, an aminoglycoside antibiotic, is related togentamicin. G418 is toxic to both prokaryotic and eukaryoticcells. It is used primarily for the selection of eukaryoticexpression vectors bearing the related resistance genes.Recommended concentration varies by cell type; in mammaliancells, 400 mg/L is recommended for initial selection, and thenreduced to 200 mg/L for culture maintenance.
Ships on blue ice. Store refrigerated at 2 to 8°C
G418 is also known by the trademark Geneticin®, as registered toInvitrogen Corporation.
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