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Tocris/Ned K/5976/10/10 mg
  • Tocris/Ned K/5976/10/10 mg

Tocris/Ned K/5976/10/10 mg

价格: ¥3540.00 市场价: 5900.00
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货号: 5976
品牌: Tocris
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    • Description:NAADPsignalinginhibitor
      ChemicalName:(1R,3S)-1-[3-[[4-(2-Cyanophenyl)piperazin-1-yl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylicacid
      Purity:≥98%(HPLC)
      BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

      BiologicalActivity

      NAADPinhibitor.PreventsCa2+oscillationsinratcardiomyocytesinvitroduringsimulatedischemiaandreperfusion,butexhibitsnosignificanteffectonCa2+sparks.Significantlyreducesinfarctsizeinratcardiacischemia/reperfusionmodelinvivo.

      TechnicalData

      M.Wt521.61
      FormulaC31H31N5O3
      StorageStoreat-20°C
      Purity≥98%(HPLC)
      PubChemID127021041
      InChIKeyLMTWTJMBOFXQTH-LITSAYRRSA-N
      SmilesO=C(O)[C@H]1N[C@H](C2=CC=C(OC)C(CN3CCN(C4=CC=CC=C4C#N)CC3)=C2)C5=C(C(C=CC=C6)=C6N5)C1

      Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

      AllTocrisproductsareintendedforlaboratoryresearchuseonly.

      SolubilityData

      SolventMaxConc.mg/mLMaxConc.mM
      Solubility
      DMSO26.0850
      ethanol10.4320

      PreparingStockSolutions

      Thefollowingdataisbasedontheproductmolecularweight521.61.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

      Concentration/SolventVolume/Mass1mg5mg10mg
      1mM1.92mL9.59mL19.17mL
      5mM0.38mL1.92mL3.83mL
      10mM0.19mL0.96mL1.92mL
      50mM0.04mL0.19mL0.38mL