BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
PotentDDHD2inhibitor(IC50=1.3nM).SelectiveforDDHD2over40otherserinehydrolases,butdoesexhibitcross-reactivitywithABHD6.Activeinvivo.Increasesbraintriacylglycerollevelsinmice.
LicensingInformation
SoldunderlicensefromTheScrippsResearchInstitute
TechnicalData
M.Wt | 458.48 |
Formula | C24H25F3N4O2 |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 1632236-44-2 |
PubChemID | 126970670 |
InChIKey | FYOYNRLSBYWAHL-UHFFFAOYSA-N |
Smiles | O=C(N(C1CCCCC1)CCC2=CC=CC=C2)N(N=C3)N=C3C(C=C4)=CC=C4OC(F)(F)F |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM |
---|
Solubility |
---|
DMSO | 45.85 | 100 |
ethanol | 45.85 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight458.48.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|
1mM | 2.18mL | 10.91mL | 21.81mL |
5mM | 0.44mL | 2.18mL | 4.36mL |
10mM | 0.22mL | 1.09mL | 2.18mL |
50mM | 0.04mL | 0.22mL | 0.44mL |