Tocris/C-DIM 12/5821/10/10 mg188bio精品生物—专注于实验室精品爆款的电商平台

BiologicalActivity

Nurr1activator.InhibitsNF-κBandcytokineexpressioninmicroglialcellsbystABIlizingnuclearcorepressorproteins,whichreducesbindingofp65toinflammatorygenepromoters.NeuroprotectiveinamouseParkinson'sdiseasemodel.Orallybioavailable.

TechnicalData

M.Wt	356.85
Formula	C₂₃H₁₇ClN₂
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	178946-89-9
PubChemID	5302583
InChIKey	LTLRXTDMXOFBDW-UHFFFAOYSA-N
Smiles	ClC1=CC=C(C(C2=CNC3=C2C=CC=C3)C4=CNC5=C4C=CC=C5)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	35.69	100
	ethanol	35.69	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight356.85.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.8mL	14.01mL	28.02mL
5mM	0.56mL	2.8mL	5.6mL
10mM	0.28mL	1.4mL	2.8mL
50mM	0.06mL	0.28mL	0.56mL

MolarityCalculator

Calculatethemass,volume,orconcentrationrequiredforasolution.

ReconstitutionCalculator

Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.

Volume(toaddtovial)

DilutionCalculator

Calculatethedilutionrequiredtoprepareastocksolution.