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p18INKinhibitor.Potentlypromoteshematopoieticstemcell(HSC)expansion(ED50=5.21nM).Exhibitsnoeffectonleukemiacellproliferation.
NSC23005sodiumisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Thefollowingdataisbasedontheproductmolecularweight305.33.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Referencesarepublicationsthatsupporttheproducts'biologicalactivity.
Xieetal(2015)DiscoveryofnovelINK4Csmall-moleculeinhibitorstopromotehumanandmurinehematopoieticstemcellexvivoexpansion.Sci.Rep.518115PMID:26681454
Keywords:NSC23005sodium,supplier,NSC23005,sodium,potently,promotes,HSC,expansion,p18INK,inhibitors,inhibits,cell,cycle,G1,phase,hematopoietic,stem,cells,Stem,Cell,Proliferation,Cell,Cycle,Inhibitors,Stem,Cell,Proliferation,TocrisBioscience
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