Tocris/M62812/5705/10/10 mg188bio精品生物—专注于实验室精品爆款的电商平台

BiologicalActivity

TLR4inhibitor.InhibitsLPS-inducedNF-κBactivationinHEK293cells(IC₅₀=2.4μg/mL).AlsoinhibitsLPS-inducedcytokineproductionandprocoagulanteffectsinPBMCsandHUVECs.Prolongssurvivalinamousesepticshockmodel.

TechnicalData

M.Wt	330.23
Formula	C₁₃H₁₁N₃OS.2HCl
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	613263-00-6
PubChemID	44224214
InChIKey	SMTKPLISDFNJDJ-UHFFFAOYSA-N
Smiles	NC1=CC=CC=C1OC2=CC=C3C(SN=C3N)=C2.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	16.51	50
	water	33.02	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight330.23.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.03mL	15.14mL	30.28mL
5mM	0.61mL	3.03mL	6.06mL
10mM	0.3mL	1.51mL	3.03mL
50mM	0.06mL	0.3mL	0.61mL

MolarityCalculator

Calculatethemass,volume,orconcentrationrequiredforasolution.

ReconstitutionCalculator

Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.

Volume(toaddtovial)

DilutionCalculator

Calculatethedilutionrequiredtoprepareastocksolution.