Tocris/AR-C 141990 hydrochloride/5658/1/1 mg188bio精品生物—专注于实验室精品爆款的电商平台

BiologicalActivity

Monocarboxylatetransporter(MCT1)inhibitor(pK_i=7.6.Exhibitsapproximately10-foldselectivityforMCT1overMCT2andnosignificantactivityagainstMCT3or4.Inhibitsgraftversushostresponseandprolongscardiacgraftsurvivalinaratmodel.Immunosuppressant.AlsoinhibitsbrainpenetrationofGHBanalogHOCPCA.

TechnicalData

M.Wt	529.05
Formula	C₂₆H₂₈N₄O₄S.HCl
Storage	Storeat-20°C
Purity	≥98%(HPLC)
Smiles	O=C(N1C[C@H](O)CC1)C2=C(CC3=C4C(C=CC=C4)=NC=C3)SC(N5CC(C)C)=C2C(N(C)C5=O)=O.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	49.26	100
	ethanol	49.26	100
	water	49.26	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight529.05.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.89mL	9.45mL	18.9mL
5mM	0.38mL	1.89mL	3.78mL
10mM	0.19mL	0.95mL	1.89mL
50mM	0.04mL	0.19mL	0.38mL

MolarityCalculator

Calculatethemass,volume,orconcentrationrequiredforasolution.

ReconstitutionCalculator

Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.

Volume(toaddtovial)

DilutionCalculator

Calculatethedilutionrequiredtoprepareastocksolution.