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Tocris/QAQ dichloride/5470/10/10 mg
  • Tocris/QAQ dichloride/5470/10/10 mg

Tocris/QAQ dichloride/5470/10/10 mg

价格: ¥2220.00 市场价: 3700.00
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货号: 5470
品牌: Tocris
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    • Description:PhotoswitchableNav,KvandCavchannelblocker
      ChemicalName:2,2'-[1,2-Diazenediylbis(4,1-phenyleneimino)bis[N,N,N-triethyl-2-oxo-ethanaminium]dichloride
      Purity:≥98%(HPLC)
      BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

      BiologicalActivity

      PhotoswitchableNav,CavandKvchannelblocker.Blockschannelsinthetransconformation.Switchesconformationfromcistotransat500nmandtranstocisat380nm.Normallymembraneimpermeant,butentersnociceptiveneuronsviaionchannelsactivatedbynoxiousstimuli,particularlyTRPV1.ExhibitsopticallyreversIBLelocalanesthesiainrats.

      TechnicalData

      M.Wt567.59
      FormulaC28H44Cl2N6O2
      StorageStoreat-20°C
      Purity≥98%(HPLC)
      PubChemID91826091
      InChIKeyVHURBRSYOFCHNY-UHFFFAOYSA-N
      SmilesO=C(C[N+](CC)(CC)CC)NC(C=C2)=CC=C2/N=N/C1=CC=C(NC(C[N+](CC)(CC)CC)=O)C=C1.[Cl-].[Cl-]

      Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

      AllTocrisproductsareintendedforlaboratoryresearchuseonly.

      SolubilityData

      SolventMaxConc.mg/mLMaxConc.mM
      Solubility
      DMSO5.6810
      water28.3850

      PreparingStockSolutions

      Thefollowingdataisbasedontheproductmolecularweight567.59.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

      Concentration/SolventVolume/Mass1mg5mg10mg
      1mM1.76mL8.81mL17.62mL
      5mM0.35mL1.76mL3.52mL
      10mM0.18mL0.88mL1.76mL
      50mM0.04mL0.18mL0.35mL