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Tocris/Bioymifi/5372/5/5 mg

价格: ¥1308.00 市场价: 2180.00
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货号: 5372
品牌: Tocris
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    • Description:DR5(TRAILreceptor)agoNIST;inducesapoptosis
      ChemicalName:5-[5-[[(5Z)-3-(4-Bromophenyl)-2-imino-4-oxo-5-thiazolidinylidene]methyl]-2-furanyl]-1H-isoindole-1,3(2H)-dione
      Purity:≥97%(HPLC)
      BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

      BiologicalActivity

      DR5(TRAILreceptor)agonist.DirectlybindsextracellulardomainofDR5(Kd=1.2μM)andinducestheformationofDR5aggregates.Inducesapoptosisofglioblastomacells.

      TechnicalData

      M.Wt494.32
      FormulaC22H12BrN3O4S
      StorageStoreat+4°C
      Purity≥97%(HPLC)
      CASNumber1420071-30-2
      PubChemID70678419
      InChIKeyULBOWKXOFOTCMU-NLDKGBHCSA-N
      SmilesBrC1=CC=C(N3C(/C(SC3=N)=C/C2=CC=C(C4=CC=C(C(NC5=O)=O)C5=C4)O2)=O)C=C1

      Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

      AllTocrisproductsareintendedforlaboratoryresearchuseonly.

      SolubilityData

      SolventMaxConc.mg/mLMaxConc.mM
      Solubility
      DMSO0.491mMwithgentlewarming

      PreparingStockSolutions

      Thefollowingdataisbasedontheproductmolecularweight494.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

      Concentration/SolventVolume/Mass1mg5mg10mg
      1mM2.02mL10.11mL20.23mL
      5mM0.4mL2.02mL4.05mL
      10mM0.2mL1.01mL2.02mL
      50mM0.04mL0.2mL0.4mL