Glutamyl endopeptidase (Glu-C) is an enzyme from Staphylococcusaureus strain V8 that hydrolizes peptide bonds formed on thecarboxyl terminal side of aspartate and glutamate amino acidresidues. Glu-C is pathogenic to human tissue and functionsduring adherence and colonization of host cells. Glu-C protectsagainst host defense mechanisms by fragmenting humanimmunoglobulins IgG, IgM, and IgA.
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