Epidermal Growth Factor (EGF) is a growth factor that stimulatesthe proliferation of epithelial and epidermal cells. EGF familymembers are characterized by three intramolecular disulfide bondsand can bind to four different receptor tyrosine kinases known asEGFR/ErbB1, ErbB2, ErbB3, and ErbB4. Recombinant mouse EGF is anon-glycosylated protein, containing 53 amino acids, including 3intra-moleuclar disulfide-bonds and having a molecular mass of 6kDa.
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