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Tocris/CaCCinh-A01/4877/10/10 mg
  • Tocris/CaCCinh-A01/4877/10/10 mg

Tocris/CaCCinh-A01/4877/10/10 mg

价格: ¥1668.00 市场价: 2780.00

货号: 4877/10
品牌: Tocris
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    • Description:Calcium-activatedchloridechannel(CaCC)inhibitor
      ChemicalName:6-(1,1-Dimethylethyl)-2-[(2-furanylcarbonyl)amino]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylicacid
      Purity:≥99%(HPLC)
      BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

      BiologicalActivity

      Calcium-activatedchloridechannel(CaCC)inhibitor(IC50~10μM).InhibitsCaCCcurrentsinhumanbronchialandintestinalcells.AlsoinhibitsTMEM16Achannels(IC50=2.1μM,inTMEM16A-expressingFRTcells).

      CompoundLibraries

      CaCCinh-A01isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

      TechnicalData

      M.Wt347.43
      FormulaC18H21NO4S
      StorageStoreat-20°C
      Purity≥99%(HPLC)
      CASNumber407587-33-1
      PubChemID2898877
      InChIKeyACLUEOBQFRYTQS-UHFFFAOYSA-N
      SmilesCC(C)(C)C1CCC2=C(SC(NC(C3=CC=CO3)=O)=C2C(O)=O)C1

      Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

      AllTocrisproductsareintendedforlaboratoryresearchuseonly.

      SolubilityData

      SolventMaxConc.mg/mLMaxConc.mM
      Solubility
      DMSO34.74100
      ethanol3.4710mMwithgentlewarming

      PreparingStockSolutions

      Thefollowingdataisbasedontheproductmolecularweight347.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

      Concentration/SolventVolume/Mass1mg5mg10mg
      1mM2.88mL14.39mL28.78mL
      5mM0.58mL2.88mL5.76mL
      10mM0.29mL1.44mL2.88mL
      50mM0.06mL0.29mL0.58mL

      ProductDatasheets

      CertificateofAnalysis/ProductDatasheet
      SafetyDatasheet

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