Tocris/Q94 hydrochloride/4755/10/10 mg188bio精品生物—专注于实验室精品爆款的电商平台

BiologicalActivity

PAR₁negativeallostericmodulator(IC₅₀=916nM);inhibitsPAR₁-Gα_qinteraction.SelectiveforPAR₁overPAR₂.Blocksthrombin-inducedintracellularcalciummobilization(IC₅₀=10.3nM),CCL2expression,ERK1/2andMLCphosphorylation,andIP₃productionincells.

TechnicalData

M.Wt	369.29
Formula	C₂₁H₁₇ClN₂.HCl
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	1052076-77-3
PubChemID	16258217
InChIKey	WXIWQTVPWYFEHP-UHFFFAOYSA-N
Smiles	ClC(C=C4)=CC=C4CN2C1=CC=CC=C1N=C2CC3=CC=CC=C3.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	18.46	50
	ethanol	18.46	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight369.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.71mL	13.54mL	27.08mL
5mM	0.54mL	2.71mL	5.42mL
10mM	0.27mL	1.35mL	2.71mL
50mM	0.05mL	0.27mL	0.54mL

MolarityCalculator

Calculatethemass,volume,orconcentrationrequiredforasolution.

ReconstitutionCalculator

Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.

Volume(toaddtovial)

DilutionCalculator

Calculatethedilutionrequiredtoprepareastocksolution.