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Amyloid-β(Aβ)aggregationinhibitor;blocksAβ(1-42)aggregationandprotectsneuronalcelllinesexposedtoAβ(1-42).ReducesAβoligomer-inducedLTPandmemorydeficitsinvivo.
SEN1269isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Thefollowingdataisbasedontheproductmolecularweight322.36.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Referencesarepublicationsthatsupporttheproducts'biologicalactivity.
Scopesetal(2012)Aβoligomertoxicityinhibitorprotectsmemoryinmodelsofsynaptictoxicity.Br.J.Pharmacol.167383PMID:22913627
Keywords:SEN1269,supplier,SEN1269,Amyloid-β,(Aβ),aggregation,inhibitors,inhibits,LTP,memory,Alzheimer's,amyloidbeta,amyloidb,Amyloid,Beta,Peptides,Amyloid,Beta,Peptides,TocrisBioscience
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