Overview | ApotentagoNISTandassumedendogenousligandofGPR55,showntoinducerapidphosphorylationofp38mitogen-activatedproteinkinase(MAPK)anditsdownstreamactivatingtranscriptionfactor2(ATF2)inbothGPR55-transfectedHEK293cells,andinIM-9lymphoblastoidcellsnaturallyexpressingGPR55at1uM,whilehavingnoeffectonvector-transfectedcells.Inaddition,showntoenhanceseruminducedcellmigrationinMCF-7cellsoverexpressingGPR55. |