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GPR35agonist(pEC50valuesare5.13and5.86forratandhumanGPR35orthologs,respectively).
TCS3035isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Thefollowingdataisbasedontheproductmolecularweight279.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Referencesarepublicationsthatsupporttheproducts'biologicalactivity.
Jenkinsetal(2011)AgonistactivationoftheGprotein-coupledreceptorGPR35involvestransmembranedomainIIIandistransducedviaGα13andβ-arrestin-2.Br.J.Pharmacol.162733PMID:20958291
Keywords:TCS3035,supplier,TCS3035,GPR35,G-protein,coupled,receptors,agonists,GPR35,GPR35,TocrisBioscience
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