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Neuroprotectivepeptidethatbindstoamyloidbeta(Aβ).ProtectsneuronsagainsttoxiceffectsofAβ(1-42)invitroandinvivo.PotentialtherapeuticinthetreatmentofAlzheimer'sDisease.
| M.Wt | 652.75 |
| Formula | C33H44N6O8 |
| Sequence | LPYFD-NH2 (Modifications:Asp-5=C-terminalamide) |
| Storage | Storeat-20°C |
| CASNumber | 700361-48-4 |
| PubChemID | 90488910 |
| InChIKey | IZXBZWOUOODINS-IRGGMKSGSA-N |
| Smiles | [H]N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(O)=O)C(N)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solubility | Solubleto2mg/mlin10%acetonitrile/water |
Thefollowingdataisbasedontheproductmolecularweight652.75.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.53mL | 7.66mL | 15.32mL |
| 5mM | 0.31mL | 1.53mL | 3.06mL |
| 10mM | 0.15mL | 0.77mL | 1.53mL |
| 50mM | 0.03mL | 0.15mL | 0.31mL |
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