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Tocris/Dolastatin 10 trifluoroacetate/3375/1/1 mg
  • Tocris/Dolastatin 10 trifluoroacetate/3375/1/1 mg

Tocris/Dolastatin 10 trifluoroacetate/3375/1/1 mg

价格: ¥2148.00 市场价: 3580.00

货号: 3375/1
品牌: Tocris
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    • Description:Tubulinpolymerizationinhibitor
      ChemicalName:N,N-Dimethyl-L-valyl-N-[(1S,2R)-2-methoxy-4-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(2-thiazol)ethyl]amino]propyl]-1-pyrrolidinyl]-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl--valinamidetrifluoroacetate
      Purity:≥95%(HPLC)
      BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

      BiologicalActivity

      Tubulinpolymerizationinhibitor.NoncompetitivelyinhibitsbindingofrADIolabeledvincristinetotubulin(Ki=1.4μM)andinducestubulinaggregationinvitro.

      TechnicalData

      M.Wt899.11
      FormulaC42H68N6O6S.CF3CO2H
      StorageStoreat-20°C
      Purity≥95%(HPLC)
      PubChemID9810929
      InChIKeyOFDNQWIFNXBECV-VFSYNPLYSA-N
      SmilesO=C(C[C@@H](OC)[C@@H](N(C)C([C@H](C(C)C)NC([C@@H](N(C)C)C(C)C)=O)=O)[C@@H](C)CC)N1[C@@]([C@H](OC)[C@@H](C)C(N[C@@H](CC3=CC=CC=C3)C2=NC=CS2)=O)([H])CCC1.FC(C(O)=O)(F)F

      Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

      AllTocrisproductsareintendedforlaboratoryresearchuseonly.

      SolubilityData

      SolubilitySolubleinDMSO

      PreparingStockSolutions

      Thefollowingdataisbasedontheproductmolecularweight899.11.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

      Concentration/SolventVolume/Mass1mg5mg10mg
      1mM1.11mL5.56mL11.12mL
      5mM0.22mL1.11mL2.22mL
      10mM0.11mL0.56mL1.11mL
      50mM0.02mL0.11mL0.22mL

      ProductDatasheets

      CertificateofAnalysis/ProductDatasheet
      SafetyDatasheet

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