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Tocris/Tandospirone hydrochloride/2854/10/10 mg
  • Tocris/Tandospirone hydrochloride/2854/10/10 mg

Tocris/Tandospirone hydrochloride/2854/10/10 mg

价格: ¥1668.00 市场价: 2780.00
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货号: 2854
品牌: Tocris
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    • Description:Selective5-HT1ApartialagoNIST
      AlternativeNames:SM-3997
      ChemicalName:(3aR,4S,7R,7aS)-rel-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dionehydrochloride
      Purity:≥98%(HPLC)
      BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

      BiologicalActivity

      5-HT1Areceptorpartialagonist(Ki=27nM)thatdisplaysselectivityover5-HT2,5-HT1C,α1,α2,D1andD2receptors(Kivaluesrangingfrom1300-41000nM).Inactiveat5-HTuptakesites,5-HT1B,β-adrenergic,muscarinicandbenzodiazepinereceptors.Displaysanxiolyticactivity.

      CompoundLibraries

      TandospironehydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

      TechnicalData

      M.Wt419.95
      FormulaC21H29N5O2.HCl
      StorageStoreat+4°C
      Purity≥98%(HPLC)
      CASNumber99095-10-0
      PubChemID13422623
      InChIKeyACVFJYKNBOHIMH-DPFKZJTMSA-N
      Smiles[H][C@]13[C@](C(N(CCCCN4CCN(C5=NC=CC=N5)CC4)C3=O)=O)([H])[C@@H]2CC[C@H]1C2.Cl

      Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

      AllTocrisproductsareintendedforlaboratoryresearchuseonly.

      SolubilityData

      SolventMaxConc.mg/mLMaxConc.mM
      Solubility
      DMSO41.99100
      water41.99100

      PreparingStockSolutions

      Thefollowingdataisbasedontheproductmolecularweight419.95.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

      Concentration/SolventVolume/Mass1mg5mg10mg
      1mM2.38mL11.91mL23.81mL
      5mM0.48mL2.38mL4.76mL
      10mM0.24mL1.19mL2.38mL
      50mM0.05mL0.24mL0.48mL