Chemical Name: (2S)-2-(6-Methoxy-2-naphthyl)propanoic acid sodium salt
Purity: ≥99% (HPLC)
Biological Activity
Technical Data
Solubility
Calculators
Datasheets
References
Biological Activity
Non-selective cyclooxygenase (COX) inhibitor that displays anti-inflammatory, antipyretic and analgesic effects. Has a neuroprotective role against colchicine-induced cognitive impairment and oxidative stress.
Technical Data
M. Wt
252.24
Formula
C14H13NaO3
Storage
Desiccate at RT
Purity
≥99% (HPLC)
CAS Number
26159-34-2
PubChem ID
23681059
InChI Key
CDBRNDSHEYLDJV-FVGYRXGTSA-M
Smiles
[Na+].COC1=CC=C2C=C(C=CC2=C1)[C@H](C)C([O-])=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
Solvent
Max Conc. mg/mL
Max Conc. mM
Solubility
water
25.22
100
Preparing Stock Solutions
The following data is based on the product molecular weight 252.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass
1 mg
5 mg
10 mg
1 mM
3.96 mL
19.82 mL
39.64 mL
5 mM
0.79 mL
3.96 mL
7.93 mL
10 mM
0.4 mL
1.98 mL
3.96 mL
50 mM
0.08 mL
0.4 mL
0.79 mL
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Product Datasheets
Certificate of Analysis / Product Datasheet
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References
References are publications that support the products' biological activity.
Dhiret al (2006) Protective effect of naproxen (non-selective COX-inhibitor) or rofecoxib (selective COX-2 inhibitor) on immobilization stress-induced behavioral and biochemical alterations in mice. Eur.J.Pharmacol. 535 192 PMID: 16522321
Kumaret al (2006) Differential effects of cyclooxygenase inhibitors on intracerebroventricular colchicine-induced dysfunction and oxidative stress in rats. Eur.J.Pharmacol. 551 58 PMID: 17027965