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Tocris/Xaliproden hydrochloride/2491/50/50 mg
  • Tocris/Xaliproden hydrochloride/2491/50/50 mg

Tocris/Xaliproden hydrochloride/2491/50/50 mg

价格: ¥7548.00 市场价: 12580.00

货号: 2491/50
品牌: Tocris
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    • Description:Orallyactive,highaffinity5-HT1AagoNIST
      AlternativeNames:SR57746A
      ChemicalName:1,2,3,6-Tetrahydro-1-[2-(2-naphthalenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]-pyridinehydrochloride
      Purity:≥99%(HPLC)
      BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

      BiologicalActivity

      Orallyactive,fullagonistat5-HT1Areceptors.Bindsrat5-HT1Awithhighaffinity(Ki=2.0nM)andis>300-foldselectiveoverother5-HTreceptorsubtypes(IC50>650nM).IncreasesmotoneuronsurvivalandpromoteseffectsofNGFonneuriteoutgrowthinvitro.Displaysneurotrophicactivityinseveralneurodegenerativemodelsinvivo. .

      CompoundLibraries

      XaliprodenhydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

      TechnicalData

      M.Wt417.9
      FormulaC24H22F3N.HCl
      StorageDesiccateatRT
      Purity≥99%(HPLC)
      CASNumber90494-79-4
      PubChemID128918
      InChIKeyWVHBEIJGAINUBW-UHFFFAOYSA-N
      SmilesCl.FC(F)(F)C1=CC(=CC=C1)C1=CCN(CCC2=CC=C3C=CC=CC3=C2)CC1

      Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

      AllTocrisproductsareintendedforlaboratoryresearchuseonly.

      SolubilityData

      SolventMaxConc.mg/mLMaxConc.mM
      Solubility
      DMSO41.79100
      ethanol8.3620

      PreparingStockSolutions

      Thefollowingdataisbasedontheproductmolecularweight417.9.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

      Concentration/SolventVolume/Mass1mg5mg10mg
      1mM2.39mL11.96mL23.93mL
      5mM0.48mL2.39mL4.79mL
      10mM0.24mL1.2mL2.39mL
      50mM0.05mL0.24mL0.48mL

      ProductDatasheets

      CertificateofAnalysis/ProductDatasheet
      SafetyDatasheet

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