Tocris/Xaliproden hydrochloride/2491/10/10 mg188bio精品生物—专注于实验室精品爆款的电商平台

BiologicalActivity

Orallyactive,fullagonistat5-HT_1Areceptors.Bindsrat5-HT_1Awithhighaffinity(K_i=2.0nM)andis>300-foldselectiveoverother5-HTreceptorsubtypes(IC₅₀>650nM).IncreasesmotoneuronsurvivalandpromoteseffectsofNGFonneuriteoutgrowthinvitro.Displaysneurotrophicactivityinseveralneurodegenerativemodelsinvivo. .

CompoundLibraries

XaliprodenhydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	417.9
Formula	C₂₄H₂₂F₃N.HCl
Storage	DesiccateatRT
Purity	≥99%(HPLC)
CASNumber	90494-79-4
PubChemID	128918
InChIKey	WVHBEIJGAINUBW-UHFFFAOYSA-N
Smiles	Cl.FC(F)(F)C1=CC(=CC=C1)C1=CCN(CCC2=CC=C3C=CC=CC3=C2)CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	41.79	100
	ethanol	8.36	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight417.9.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.39mL	11.96mL	23.93mL
5mM	0.48mL	2.39mL	4.79mL
10mM	0.24mL	1.2mL	2.39mL
50mM	0.05mL	0.24mL	0.48mL

MolarityCalculator

Calculatethemass,volume,orconcentrationrequiredforasolution.

ReconstitutionCalculator

Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.

Volume(toaddtovial)

DilutionCalculator

Calculatethedilutionrequiredtoprepareastocksolution.