GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!
RecombinantMurine Chemokine (C-C motif) Ligand 19 (CCL19)MacrophageInflammatory Protein 3, Beta (MIP3B, MIP-3β)SmallInducible Cytokine Subfamily A Member 17 (SCYA17)Exodus 3,Exodus-3EBI1Ligand Chemokine (ELC)ChemokineBeta 11 (CkB11, Ck-β-11)
CCL19 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed by dendritic cells in lymph nodes, as well as in spleen and thymus tissue. Expression of CCL19 is upregulated by IFNG and TNF-alpha. CCL19 has shown to be chemotactic for T-cells and B-cells, as well as CFU granulocyte macrophages. It plays a role in mobilization of dendritic cells from the epidermis to lymph nodes and development of local lymphoid tissues. CCL19 is a ligand for CCR7 (EBI1), as well as the atypical chemokine receptors CCRL1 and CCRL2.
Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.
Source: Escherichia coli
MW: ~9.2 kDa (83 aminoacids)
Purity: >97% by SDS-PAGEand HPLC analyses
Biological Activity: Fully biologicallyactive when compared to standard. The biological activity determined by achemotaxis bioassay using human mature dendritic cells is in a concentrationof 10-100 ng/ml.
Storage/Handling: Store desiccated at-20°C.
MGD: 1346316
NOT FOR HUMAN USE!
Additional resources for this protein may be found at:OMIM
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