GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!
RecombinantHuman Chemokine (C-C motif) Ligand 18 (CCL18)Pulmonaryand Activation Regulated Chemokine (PARC)SmallInducible Cytokine Subfamily A Member 18 (SCYA18)AlternativeMacrophage Activation-Associated CC Chemokine 1 (AMAC1, AMAC-1)DendriticCell Chemokine 1 (DCCK1, DC-CK1)MacrophageInflammatory Protein 4 (MIP4, MIP-4)
CCL18 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed constitutively in lung tissues and transiently in alveolar macrophages and follicular dendritic cells induced by IL4, IL10, IL13, LPS, or PMA. Expression of CCL18 is inhibited by IFNG. CCL18 is chemotactic for activated T-lymphocytes, non-activated lymphocytes, and basophils and likely plays a role in initiation of immune responses. It is a ligand for CCR8 and GPER1.
Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.
Source: Escherichia coli
MW: ~7.9 kDa (69 aminoacids)
Purity: >97% by SDS-PAGEand HPLC analyses
Biological Activity: Fully biologicallyactive when compared to standard. The biological activity determined by achemotaxis bioassay using human T-lymphocytes is in a concentration of 1-10ng/ml.
Storage/Handling: Store desiccated at-20°C.
HGNC: 10616
NOT FOR HUMAN USE!
Additional resources for this protein may be found at:OMIM
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