mGM-CSF is produced in response to a number of inflammatorymediators by mesenchymalcells present in the hemopoieticenvironment and at peripheral sites of inflammation.It is able tostimulate the production of neutrophilic granulocytes,macrophages and mixed granulocyte-macrophage colonies from bonemarrow cells and can stimulate the formation of eosinophilcolonies from fetal liver progenitor cells.GM-CSF can alsostimulate some functional activities in mature granulocytes andmacrophages.GM-CSF receptors show significant homologies withother receptors for hematopoietic growth factors, includingIL2-beta, IL-3, IL-6, IL-7, EPO and the prolactin receptors. Thiscarrier-free product is a recombinant protein expressed in E.coli.
Ships ambient. Store frozen -20 to -10C.
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