BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
α1-adrenoceptorantagonistand5-HT1Areceptoragonist(pIC50valuesare6.13and6.4respectively).Clinicallyusedhypotensiveagent.
TechnicalData
M.Wt | 423.94 |
Formula | C20H29N5O3.HCl |
Storage | DesiccateatRT |
Purity | ≥99%(HPLC) |
CASNumber | 64887-14-5 |
PubChemID | 167980 |
InChIKey | KTMLZVUAXJERAT-UHFFFAOYSA-N |
Smiles | Cl.COC1=CC=CC=C1N1CCN(CCCNC2=CC(=O)N(C)C(=O)N2C)CC1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM |
---|
Solubility |
---|
phosphatebufferedsaline | 10.6 | 25 |
water | 21.2 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight423.94.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|
1mM | 2.36mL | 11.79mL | 23.59mL |
5mM | 0.47mL | 2.36mL | 4.72mL |
10mM | 0.24mL | 1.18mL | 2.36mL |
50mM | 0.05mL | 0.24mL | 0.47mL |