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Tocris/Noladin ether/1411/5/5 mg
  • Tocris/Noladin ether/1411/5/5 mg

Tocris/Noladin ether/1411/5/5 mg

价格: ¥1668.00 市场价: 2780.00
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货号: 1411
品牌: Tocris
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    • Description:EndogenousagoNISTforCB1andGPR55
      AlternativeNames:HU310,2-Arachidonylglycerolether
      ChemicalName:2-[(5Z,8Z,11Z,14Z)-Eicosatetraenyloxy]-1,3-propanediol
      BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

      BiologicalActivity

      EndogenousagonistfortheGPR55andCB1receptors(EC50valuesare10and37nMrespectively)thatdisplaysselectivityoverCB2receptors(Kivaluesare21.2nMand>3mMatCB1andCB2respectively).Causessedation,hypothermia,intestinalimmobilityandmildantinociceptioninvivo.AttenuatessensoryneurotransmissioninratmesentericarteriesviaGPR55.

      TechnicalData

      M.Wt364.57
      FormulaC23H40O3
      StorageDesiccateat-20°C
      CASNumber222723-55-9
      PubChemID6483057
      InChIKeyCUJUUWXZAQHCNC-DOFZRALJSA-N
      SmilesCCCCCC=C/CC=C/C/C=CC/C=CCCCCOC(CO)CO

      Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

      AllTocrisproductsareintendedforlaboratoryresearchuseonly.

      SolubilityData

      SolubilitySolubleinethanol(suppliedpre-dissolvedinanhydrousethanol,5mg/ml)

      PreparingStockSolutions

      Thefollowingdataisbasedontheproductmolecularweight364.57.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

      Concentration/SolventVolume/Mass1mg5mg10mg
      1mM2.74mL13.71mL27.43mL
      5mM0.55mL2.74mL5.49mL
      10mM0.27mL1.37mL2.74mL
      50mM0.05mL0.27mL0.55mL