Capacity:for2×109totalcellsOverview
TheCD31MicroBeads,mouse,havebeendevelopedforthepositiveselectionordepletionofCD31
+endothelialcellsfromsingle-cells
USPensionsofmousetissues.
Details
Backgroundinformation
TheCD31antibodyreactswiththecellsurfaceproteinCD31.ThemurineCD31antigenisalsoknownasPECAM-1.CD31isasingle-passtypeImembraneproteincontainingsixIg-likeC2-typedomainsandfunctionsascelladhesionmolecule1.Itispresentonmatureendothelialcellsaswellasonmostleukocytesubtypesandplatelets2wheretheexpressionlevelcanvary.Besidesitsfunctionincelladhesion,theproteinisrequiredforleukocytetransendothelialmigration(TEM)undermostinflammatoryconditions3.
Downstreamapplications
MouseendothelialcellsisolatedwithCD31MicroBeadsareimmediatelyreadytobeusedforphenotypeanalysis,cocultureexperiments,orfunctionalstudies,forexample,intumorvascularizationresearch.
Columns
Forpositiveselection:MS,LS,orauto
MACS®Columns.Fordepletion:LDorautoMACSColumns.