Capacity:for1×109totalcellsOverview
TheAnti-MSCA-1(W8B2)MicroBeadKit,basedontheantibodycloneW8B2,wasdevelopedforthepositiveselectionofmesenchymalstromalcells(MSCs)withahighproliferativecapacity,derivedfrombonemarrowaspirates.
Details
Backgroundinformation
TheAnti-MSCA-1(W8B2)MicroBeadsrecognizethemesenchymalstromalcellantigen-1(MSCA-1),whichisidenticaltotissuenon-specificalkalinephosphatase1.
MSCA-1wasshowntoberestrictedtoMSCsintheCD271
brightpopulationinhumanbonemarrow
2.TheseCD271
brightCD45
dimMSCshaveamuchhigherclonogeniccapacitycomparedtotheCD271
+CD45
+fractioninbonemarrow.Therefore,MSCA-1isahighlyspecific
MarkertoisolateMSCswithahighproliferativepotentialfrombonemarrow.MSCA-1expressionwasnotfoundonplacenta-derivedMSCsafterculture
3.
AntibodiesagainstMSCA-1showbroadinterspeciescross-reactivity,suchasdog,pig,sheep,goatandmonkey4.
Columns
MS,LS,XS,orauto
MACS®Columns.