Capacity:for1×109totalcellsOverview
CD20MicroBeadsweredevelopedforpositiveselectionordepletionofhumanCD20+BcellsfromdifferentcellsourcessuchashumanPBMCs,bonemarrow,cellculturesorlymphoidtissues.
Details
Backgroundinformation
CD20isanon-glycosylatedtransmembraneproteinof33–37kDathatbecomesheavilyphosphorylateduponactivation
1,2.ItisexpressedexclusivelyonBcells,includingpre-Bcells,naive,mature,andactivatedBcells,Bcellblasts,andthemajorityofmalignantBcells,butnotonearlyBcell
Progenitorsorplasmacells
2,3.
Downstreamapplications
PurifiedCD20
+Bcellsmaybeusedincell
BIOLOGicalstudies,suchasanalysisofsignaltransduction,chemotaxis,allergenresponse,apoptosis,orinmolecularstudies,e.g.,subset-specificmicroarrays.
Columns
Forpositiveselection:MS,LS,XS,orauto
MACS®Columns.Fordepletion:LD,CS,D,orautoMACSColumns.