Capacity:for1×109totalcellsOverview
Anti-ErbB-2MicroBeadscanbeusedfortheenrichmentofdisseminatedepithelialErbB-2-expressingtumorcellsfromblood,bonemarrow,orleukapheresisharvest.
Details
Backgroundinformation
ErbB-2,alsoknownasHER2/neu,CD340orp185,encodesthehumanepidermalgrowthfactorreceptorwhichisoverexpressedin25–30%ofbreastcancerpatientsaswellasinvariousothertumors,e.g.ovarian,prostate,lung,colorectal,pancreatic,andgastriccancers.
Downstreamapplications
EnrichedErbB-2+cellscanbecharacterizedbyusingdifferenttechniquessuchasquantitativereal-timePCR1,immunocytochemistry,orflowcytometry.Theenrichedcellscanalsobecultured.
Columns
MS,LS,XS,orauto
MACS®Columns.