Description
AlgiMatrix™3DCultureSystemisthefirstuser-friendlynon-animal-derivedbioscaffoldforthree-dimensional(3D)cellculture.AlgiMatrix™3DCultureSystemcreatesacellculturemodelsystemthatmorecloselyreflectsnormalcellmorphologyandbehavior,tomeetresearchers"requirementsfor3Dcellcultureinfieldssuchastoxicology,drugdevelopment,cancerandstemcellresearch,developmentandmorphogenesis,tissueandorganengineering,heartdisease,diabetes,andAlzheimersdisease.
AlgiMatrix™3DCultureSystemissuppliedina96-wellformatthatfitswellintotheworkflowofbothlower-andhigher-throughputusers.Scientistscaninoculatecellsdirectlyintothesterilemicrotiterplatespreloadedwithlyophilizedalginatesponge,withnopretreatmentsorpreparationsrequired.Thecombinationofconvenience,highcapacity,andmicroscopicvisualizationmakesAlgiMatrix™3DCultureSystemanidealsolutionforbroadbasicresearchanddrugdiscoveryapplications.
Applications:
AlgiMatrix™3DCultureSystemissuitableformanycell-basedscreening,drugdiscovery,andhumancelltherapyprocedures,includingtheMulticellularTumorSpheroidAssays(MCTS),
1hepatocyte
2-4andcardiomyocyteorganogenesisstudies,
5co-culturestudies,
6high-throughputdrugscreeningassays,
1andembryonicstemcell3Ddifferentiation.
7Eachlotisperformanceandqualitytestedinacell-basedtoxicityassay.
Storage:
Roomtemperature.
References:
1.Kunz-Schughart,L.,etal.,(2004)
JBiomolecScreening9,273.
2.Dvir-Ginzberg,M.,etal.(2003)
TissueEngineering9,757.
3.Elkayam,T.,etal.(2006)
TissueEngineering12,1357.
4.Kedem,A.,etal.(2005)
TissueEngineering11,715.
5.Dar,A.,etal.(2002)
Biotechnology&Bioengineering80,305.
6.Kim,J.(2005)
SeminarsinCancerBIOLOGy15,365.
7.Gerecht-Nir,S.,etal.(2004)
Biotechnology&Bioengineering88,313.
ForResearchUseOnly.Notforuseindiagnosticprocedures.