Description
IMDM(Iscove"sModifiedDulbecco"sMedium)iswellsuitedforrapidlyproliferating,high-densitycellcultures,includingJurkat,COS-7,andmacrophagecells.WeofferavarietyofIMDMmodificationsforarangeofcellcultureapplications.Findtherightformulationusingthemediaselectortool.
ThisIMDMismodifiedasfollows:With | Without |
•L-glutamine | •α-thioglycerol |
Thecompleteformulationisavailable.
UsingIMDMIMDM,amodificationofDulbecco"sModifiedEagleMedium,includesseleniumaswellasadditionalaminoacidsandvitamins.Inaddition,thisuniquemediumlacksiron,withpotassiumnitratereplacingferricnitrate.IMDMcontainsnoproteins,lipids,orgrowthfactors.Therefore,IMDMrequiressupplementation,commonlywith10%FetalBovineSerum(FBS).IMDMusesasodiumbicarbonatebuffersystem(3.024g/L),andthereforerequiresa5–10%CO
2environmenttomaintainphysiologicalpH.
cGMPmanufacturingandqualitysystemIMDMismanufacturedatacGMP-compliantfacilitylocatedinGrandIsland,NewYork.ThefacilityisregisteredwiththeFDAasamedicaldevicemanufacturerandiscertifiedtoISO13485standards.Forsupplychaincontinuity,weofferanidenticalIMDMproductmadeinourScotlandfacility(21980-032).ThisfacilityisregisteredwiththeFDAasamedicaldevicemanufacturerandiscertifiedtotheISO13485standard.