Tocris/Brefeldin A/1231/5/5 mg188bio精品生物—专注于实验室精品爆款的电商平台

BiologicalActivity

ReversIBLeinhibitorofproteintranslocationfromtheendoplasmicreticulum(ER)totheGolgiapparatus.BlocksbindingofADP-ribosylationfactortotheGolgiapparatusandinhibitsGDP-GTPexchange.Canbeusedtoinduceautophagyinmammaliancells.AlsoenhancesCRISPR-mediatedhomology-directedrepair(HDR)efficiency~2-foldwhenappliedat100nM,inhumaninducedpluripotentstemcells(iPSCs).

CompoundLibraries

BrefeldinAisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	280.36
Formula	C₁₆H₂₄O₄
Storage	Desiccateat-20°C
Purity	≥98%(HPLC)
CASNumber	20350-15-6
PubChemID	6436187
InChIKey	KQNZDYYTLMIZCT-KFKPYADVSA-N
Smiles	[H][C@]1(C)CCCC=CC2C[C@H](O)C[C@H]2[C@H](O)C=CC(=O)O1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	14.02	50
	ethanol	2.8	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight280.36.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.57mL	17.83mL	35.67mL
5mM	0.71mL	3.57mL	7.13mL
10mM	0.36mL	1.78mL	3.57mL
50mM	0.07mL	0.36mL	0.71mL

MolarityCalculator

Calculatethemass,volume,orconcentrationrequiredforasolution.

ReconstitutionCalculator

Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.

Volume(toaddtovial)

DilutionCalculator

Calculatethedilutionrequiredtoprepareastocksolution.