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Tocris/RS 17053 hydrochloride/0985/10/10 mg
  • Tocris/RS 17053 hydrochloride/0985/10/10 mg

Tocris/RS 17053 hydrochloride/0985/10/10 mg

价格: ¥1668.00 市场价: 2780.00

货号: 0985/10
品牌: Tocris
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    • Description:α1AantagoNIST
      ChemicalName:(N-[2-(2-Cyclopropylmethoxyphenoxy)ethyl]-5-chloro-α,α-dimethyl-1H-indole-3-ethanamine)hydrochloride
      BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

      BiologicalActivity

      α1A-adrenoceptorantagonist,withveryhighaffinityforα1Areceptors(pKiandpA2estimatesof9.1-9.9)anda30-100foldselectivityovertheα1Bandα1Dsubtypes(pKiandpA2estimates7.7-7.8).

      LicensingInformation

      SoldwiththepermissionofRocheBioscience

      CompoundLibraries

      RS17053hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

      TechnicalData

      M.Wt449.42
      FormulaC24H29N2O2Cl.HCl
      StorageStoreatRT
      CASNumber169505-93-5
      PubChemID9824953
      InChIKeyQFOPFGRPNPCPBX-UHFFFAOYSA-N
      SmilesCl.CC(C)(CC1=CNC2=CC=C(Cl)C=C12)NCCOC1=C(OCC2CC2)C=CC=C1

      Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

      AllTocrisproductsareintendedforlaboratoryresearchuseonly.

      SolubilityData

      SolventMaxConc.mg/mLMaxConc.mM
      Solubility
      DMSO22.4750
      ethanol4.4910

      PreparingStockSolutions

      Thefollowingdataisbasedontheproductmolecularweight449.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

      Concentration/SolventVolume/Mass1mg5mg10mg
      1mM2.23mL11.13mL22.25mL
      5mM0.45mL2.23mL4.45mL
      10mM0.22mL1.11mL2.23mL
      50mM0.04mL0.22mL0.45mL

      ProductDatasheets

      CertificateofAnalysis/ProductDatasheet
      SafetyDatasheet

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