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Tocris/Cirazoline hydrochloride/0888/10/10 mg

价格: ¥1548.00 市场价: 2580.00

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货号: 0888/10

品牌: Tocris

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Description: Selective α₁ agonist

Chemical Name: 2-(2-Cyclopropylphenoxymethyl)imidazoline hydrochloride

Purity: ≥99% (HPLC)

Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity

Selective α₁ agonist. Also available as part of the α₁-Adrenoceptor Tocriset™ and Mixed Adrenergic Tocriset™.

Compound Libraries

Cirazoline hydrochloride is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt	252.74
Formula	C₁₃H₁₆N₂O.HCl
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	40600-13-3
PubChem ID	11957512
InChI Key	XFRXWLWUUDJHPB-UHFFFAOYSA-N
Smiles	Cl.C(OC1=C(C=CC=C1)C1CC1)C1=NCCN1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	DMSO	25.27	100
	water	25.27	100

Preparing Stock Solutions

The following data is based on the product molecular weight 252.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.96 mL	19.78 mL	39.57 mL
5 mM	0.79 mL	3.96 mL	7.91 mL
10 mM	0.4 mL	1.98 mL	3.96 mL
50 mM	0.08 mL	0.4 mL	0.79 mL

Product Datasheets

Certificate of Analysis / Product Datasheet

Safety Datasheet

References

References are publications that support the products' biological activity.

Le Rouzic et al (1995) Binding of [³H]cirazoline to an imidazoline site in rat brain and kidney membranes. Eur.J.Pharmacol. 278 261 PMID: 7589165

Gellai and Ruffolo (1987) Renal effects of selective alpha-1 and alpha-2 adrenoreceptor agonists in conscious normotensive rats. J.Pharmacol.Exp.Ther. 240 723 PMID: 2882013

Wikberg and Uklen (1990) Further characterisation of the guinea pig cerebral cortex idazoxan receptor: solubilization, distinction from the imidazole site, and demonstration of cirazoline as an idazoxan receptor-selective drug. J.Neurochem. 55 192 PMID: 1972387

Keywords: Cirazoline hydrochloride, supplier, Selective, α1, α1-adrenoceptor, alpha1-adrenoceptor, α1-adrenergic, alpha1-adrenergic, a1-adrenoceptor, a1-adrenergic, agonists, Imidazoline, ligands, Receptors, General, Imidazolines, Adrenergic, Alpha-1, Receptors, General, Imidazolines, Adrenergic, Alpha-1, Receptors, Tocris Bioscience

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