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Phosphodiesteraseinhibitor,selectiveforPDE1(IC50=21μM).Alsoblocksvoltage-gatedNa+channels.
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Thefollowingdataisbasedontheproductmolecularweight350.46.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Referencesarepublicationsthatsupporttheproducts'biologicalactivity.
Hagiwaraetal(1984)Effectofvinpocetineoncyclicnucleotidemetabolisminvascularsmoothmuscle.Biochem.Pharmacol.33453PMID:6322804
MolnarandErdo(1995)Vinpocetineisaspotentasphenytointoblockvoltage-gatedNa+channelsinratcorticalneurons.Eur.J.Pharmacol.273303PMID:7737339
MerckIndex1210128PMID:
Keywords:Vinpocetine,supplier,PDE1,inhibitors,inhibits,Na+,channel,blockers,Phosphodiesterases,Sodium,NaV,Channels,voltage-gated,voltage-dependent,Voltage-gated,Sodium,Channels,Phosphodiesterases,Voltage-gated,Sodium,Channels,TocrisBioscience
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