The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
Solvent
Max Conc. mg/mL
Max Conc. mM
Solubility
DMSO
24.55
50
ethanol
24.55
50
water
24.55
50
Preparing Stock Solutions
The following data is based on the product molecular weight 491.07. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass
1 mg
5 mg
10 mg
1 mM
2.04 mL
10.18 mL
20.36 mL
5 mM
0.41 mL
2.04 mL
4.07 mL
10 mM
0.2 mL
1.02 mL
2.04 mL
50 mM
0.04 mL
0.2 mL
0.41 mL
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Product Datasheets
Certificate of Analysis / Product Datasheet
Safety Datasheet
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References
References are publications that support the products' biological activity.
Ishibashiet al (1995) Block of P-type Ca2+ channels in freshly dissociated rat cerebellar Purkinje neurons by diltiazem and verapamil. Brain Res. 695 88 PMID: 8574653
Lacinovaet al (1995) Interaction of RO-40-5967 and verapamil with the stably expressed α1-subunit of the cardiac L-type calcium channel. J.Pharmacol.Exp.Ther. 274 54 PMID: 7616442
Ustuneset al (1996) Effects of verapamil on intimal thickening and vascular reactivity in the collared carotid artery of the rabbit. Br.J.Pharmacol. 118 1681 PMID: 8842432
Fleminget al (2011) Chemical modulators of autophagy as biological probes and potential therapeutics. Nat.Chem.Biol. 7 9 PMID: 21164513