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Tocris/Thioperamide/0644/10/10 mg
  • Tocris/Thioperamide/0644/10/10 mg

Tocris/Thioperamide/0644/10/10 mg

价格: ¥1548.00 市场价: 2580.00

货号: 0644/10
品牌: Tocris
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    • Description:H3antagoNISTandH4inverseagonist
      ChemicalName:N-Cyclohexyl-4-(imidazol-4-yl)-1-piperidinecarbothioamide
      Purity:≥99%(HPLC)
      BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

      BiologicalActivity

      PotenthistamineH3andH4antagonist/inverseagonist.Kivaluesare25and27nMforhumanrecombinantH3andH4receptorsrespectively.Blockseosinophilshapechange(IC50=1.4μM)andchemotaxis(IC50=519nM)inducedbyhistamine.Freelycrossestheblood-brainbarrier.AlsoavailableaspartoftheHistamineH3ReceptorTocriset™.

      CompoundLibraries

      ThioperamideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

      TechnicalData

      M.Wt292.44
      FormulaC15H24N4S
      StorageStoreat-20°C
      Purity≥99%(HPLC)
      CASNumber106243-16-7
      PubChemID3035905
      InChIKeyQKDDJDBFONZGBW-UHFFFAOYSA-N
      SmilesS=C(NC3CCCCC3)N(CC2)CCC2C1=CNC=N1

      Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

      AllTocrisproductsareintendedforlaboratoryresearchuseonly.

      SolubilityData

      SolventMaxConc.mg/mLMaxConc.mM
      Solubility
      DMSO29.24100
      ethanol29.24100

      PreparingStockSolutions

      Thefollowingdataisbasedontheproductmolecularweight292.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

      Concentration/SolventVolume/Mass1mg5mg10mg
      1mM3.42mL17.1mL34.2mL
      5mM0.68mL3.42mL6.84mL
      10mM0.34mL1.71mL3.42mL
      50mM0.07mL0.34mL0.68mL

      ProductDatasheets

      CertificateofAnalysis/ProductDatasheet
      SafetyDatasheet

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