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ACa2+blockerthatstrikinglyprolongscardiacactionpotentialsbyinhibitingpacemakercurrentandK+outwardcurrents.
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Thefollowingdataisbasedontheproductmolecularweight395.93.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Referencesarepublicationsthatsupporttheproducts'biologicalactivity.
Bergeretal(1991)InhibitionofpotassiumoutwardcurrentsandpacemakercurrentinsheepcardiacPurkinjefibresbytheverapamilderivativeYS-035.NaunynSchmiedebergsArch.Pharmacol.344653PMID:1775198
Deanaetal(1984)PropertiesofanewcalciumionantagoNISToncellularuptakeandmitochondrialeffluxofcalciumions.Biochem.J.218899PMID:6721841
Keywords:YS-035hydrochloride,supplier,inhibitors,inhibits,K+,outward,pacemaker,current,Potassium,Channels,Non-Selective,Non-selective,/,Other,Potassium,Channels,HCN,Channels,Non-selective,/,Other,Potassium,Channels,TocrisBioscience
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